A fan of comics since his youth, Dinan-born Fred Simon started a fanzine while still at college. Afterwards, he studied Plastic Arts in Rennes and launched the Studio Psurde with some friends.He worked on several projects with this studio, including illustrating postcards and cooperating on the collective comic album 'Si Septennat m'était Conté, that was published by Vents d'Ouest in 1988. He then moved to Rennes, where Lucien Rollin helped him getting some of his stories published in Circus magazine.
He then began a fruitful collaboration with scriptwriter David Chauvel, with whom he has created several series for Éditions Delcourt. After the detective series 'Rails' (1992-1995) and 'Le Poisson-Clown' (1997-2001), they started the children's series about the Sioux girl 'Popotka' (2002-2007).
Simon and Chauvel had their turn on Stevenson's 'Treasure Island' with the series 'L'Île au trésor' (2007-2009) and Simon subsequently made an adaptation of Jack London's 'L'Appel de la forêt' on his own in 2010. He began an association with Corine Jamar and Leo for his next series, 'Mermaid Project', that is published by Dargaud since 2012.