Although educated as a painter and decorator, Sergio Tarquinio turned to making comics in 1945. His first exploit was 'Luna d'Argento' with Editions DEA, followed by Roy d'Ami's 'Blek e Gionni'. He emigrated to Argentina in 1948, where he joined the "Group of Venice", which consisted of artists like Hugo Pratt, Ivo Pavone, Mario Faustinelli and Dino Battaglia, who were all working for Editorial Abril. Tarquinio drew covers for Misterix and created the seriesk 'Alan Blood', El Inspector Slop' and 'El Secreto de la Piramide'.