Thomas Yeates was part of the first graduating class from The Kubert School.
His first published comics work was "Preacher" a five-page backup feature in Sgt. Rock #312 (Jan. 1978). He provided spot illustrations for a Batman prose story in Detective Comics #500 (March 1981) written by Walter B. Gibson, longtime writer of The Shadow.
Yeates and Jack C. Harris briefly revived Claw the Unconquered as a backup feature in The Warlord #48-49."Dragonsword" was a backup feature by Paul Levitz and Yeates which appeared in The Warlord #51-54 (Nov. 1981–Feb. 1982).
In 1982, Yeates and writer Martin Pasko revived Swamp Thing in a new series titled Saga of the Swamp Thing.
Timespirits was created by Stephen Perry and Yeates for the Epic Comics line.
He drew the Universe X: Beasts and Universe X: Cap one-shots for Marvel in 2001. On April 1, 2012, Yeates began drawing the Prince Valiant comic strip, replacing Gary Gianni. Yeates collaborated with Sergio Aragonés and Mark Evanier on the Groo vs. Conan crossover for Dark Horse Comics 2014.