Jaime Caldéron was born in Barcelona. He learned the finer points of the profession during courses by illustrators like Enri Paixà and López Espí. Between 1994 and 2004 he worked as a commercial artist. He is a teacher and co-founder of the FEM Art Comics and Illustration School in Barcelona since 2000.
In 2004 he drew the second book of the series 'Extrahumans' from a script by López Espí. He worked with David Carbajal on the mini-series 'Siddartha' for the publihsing house Recerca. He has also worked for Sword magazine and the American publisher Alpha-Omega Comics.
In 2007 he illustrated the graphic novel 'The Lovecraftian Horror'. In Spain, he made 'La Larga Noche de los Malditos' with Antonio José Navarro for the small publishing house AM. By 2009 he became the artist for the historical series 'Les Voies du Seigneur', written by Fabrice David and Gregory Lassablière for the French publisher Soleil.