Emmanuel Moynot published his first work in the fanzine P.L.G.P.P.U.R. from 1981. In addition to his contributions for this fanzine, he drew for Elvifrance, Viper and special issues of Circus. His first album, 'l'Enfer du Jour', was published by Glénat in 1983. Two years later, he collaborated with writer Michel Schetter on the series 'Yerushalaïm', published in the magazine Vécu.
In 1989, he conceived 'La Pension des Deux-Roses' for Magic Strip. In 1992 he began the series 'Le Temps des Bombes' for Dargaud, at first on his own and later in cooperation with scriptwriter Dieter. With the same writer, he made 'Qu'ell Crève, la Charogne!' (Vents d'Ouest, 1995) and the series 'Nord-Sud' (Dargaud, 1997, later renamed to 'Vieux Fou!' for Delcourt). In 1995, he additionally developed 'L'Enfer du Jour' for the Dargaud collection Roman B.D.
In 1998, he was present at Casterman with 'Bonne Fête Maman!', followed in 1999 and 2000 by 'Pendant que tu dors, mon Amour?' and 'À Quoi tu Penses?'. In the following year, Moynot produced 'Y5/P5' for P.M.J. Editions. He began working more extensively for Glénat in the new millenium.