Eduardo Ocaña was born in Madrid, where he also studied architecture. Although he started out working as an architect, his focus shifted to comics and illustration between 1999 and 2002. In 2002-03 he produced a series of 8 issues in the fantasy collection 'Chronicas de Mesene'. In 2006 he created the 7th book in the series 'Kookabura Universe' with Sylvain Runberg for the French publisher Soleil. That same year, he published the first book in the series 'Messiah Complex', which he makes with Alex de Campi for Les Humanoïdes Associés. Since 2010 he works with Runberg again on 'Les Carnets de Darwin', published by Lombard.