Chic Stone studied at the School of Industrial Arts and the Works Projects Administration School. He had his apprenticeship in the Eisner-Iger studios in the late 1930s. He worked for Fawcett's 'Captain Marvel' in the early 1940s and then worked for most of the major comic book agencies, such as Timely and Lev Gleason. He left the comics field during the 1950s and became the art director of such magazines as True Experience and The American Salesman. He also worked for the Gray Advertising Agency and the Filmack Studios, doing storyboards for commercials.
He returned to comics in the 1960s, pencilling 'Adventures into the Unknown' for ACG between 1962 and 1967. He then became an inker of Jack Kirby's work for many years, and he did such titles as 'Fantastic Four', 'X-Men' and 'Thor'. He also freelanced for DC, where he cooperated on 'Batman' and ghosted for Bob Kane, George Papp and Sal Trapani. He was also present in Tower Comics' 'T.H.U.N.D.E.R. Agents', 'Dynamo' and 'NoMan', and in some Dell ('Flying Saucers', 'Garrison's Gorillas'), ACG ('Forbidden Worlds', 'Unknown Worlds') and Skywald (Psycho, Nightmare) publications.
During the 1980s, he worked for Archie Comics, doing superhero comics like 'Red Circle' and 'Archie Adventure Series', as well as comics with the several 'Archie' characters, such as 'Mr. Weatherbee'.