Spider-Man 2099 Miguel O'Hara enjoying a day on the beach (or so they think!) with Lyla -LYrate Lifeform Approximation - an android personal assistant modeled after Marilyn Monroe.
The character has been re-introduced this year in the Superior Spider-Man series, whose renewed popularity warranted a relaunch of the Spider-Man 2099 title in 2014.
This is certainly one of the best known image of Lyla, with this figure even used on the character's Marvel Wikia page. http://marvel.wikia.com/Lyla
This art has an image area of approximately 10" x 15" on standard 11" x 17" board.