Robinson's first major work was Box Office Poison, originally serialized by Antarctic Press and then collected into graphic novel form in 2001 by Top Shelf Productions. Box Office Poison concerns the life and trials of a group of young people in New York City (the central protagonist works in a bookstore, a job Robinson himself held for seven years.)
Robinson's second graphic novel, Tricked, also published by Top Shelf, was released in August 2005, and both Box Office Poison and Tricked have been translated into French, Spanish, Italian, Portuguese, Polish and German.
In October 2007 Alex Robinson's Lower Regions was released, a 56-page comic about "a sexy barbarian fighting monsters." Two sequels are planned for the coming years.
His next graphic novel, Too Cool to Be Forgotten, a time travel/high school story, was published by Top Shelf in July 2008, with A Kidnapped Santa Claus, adapted from a Frank L. Baum story, following in November 2009.
Along with Mike Dawson, Tony Consiglio, and a few other cartoonists, Robinson is part of a loosely associated collective called The Ink Panthers. They also have a podcast called "The Ink Panthers Show" available on iTunes. Alex also has a podcast with Pete "The Retailer" Bonavita called Star Wars Minute where they analyze, scrutinize and celebrate the Star Wars movies one minute at a time.