Isabelle was a Belgian comic series drawn by Will and written by André Franquin, Delporte and Raymond Macherot.
The comic first appeared in Spirou magazine in 1969. Created by a top team of already-famous contributors to the magazine, the series gained a small but fanatical following. The first stories were written by Franquin (of Gaston Lagaffe fame), Delporte (editor of Spirou and writer of many comics) and Macherot (creator of Sibylline).